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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAN3 All Species: 22.42
Human Site: T240 Identified Species: 32.89
UniProt: Q58A45 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q58A45 NP_787050.4 741 82181 T240 V N N P V S Q T P S S G Q V I
Chimpanzee Pan troglodytes XP_001136622 741 82148 T240 V N N P V S Q T P S S G Q V I
Rhesus Macaque Macaca mulatta XP_001097210 741 82134 T240 V N N P V S Q T P S S G Q V I
Dog Lupus familis XP_543150 987 105833 T486 V N N P V S Q T P S S G Q V I
Cat Felis silvestris
Mouse Mus musculus Q640Q5 691 76362 T227 N Y H I Y P P T A P H V A Y M
Rat Rattus norvegicus XP_002724835 883 95283 T382 A N N P V P Q T P S S G Q V I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519591 717 78728 V244 T D T T P A P V T G M V F P N
Chicken Gallus gallus XP_417120 757 83269 P257 V A N A V S Q P P S T G Q V I
Frog Xenopus laevis NP_001128699 631 68072 S167 A A H D P L G S P A S A M F N
Zebra Danio Brachydanio rerio XP_002666687 799 86684 Q299 V P T T A P D Q A G G A H I I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_728797 788 85176 S244 G A G P G E K S P P H G M T P
Honey Bee Apis mellifera XP_623553 607 67474 S143 K P T K P P S S N S S S A P S
Nematode Worm Caenorhab. elegans P34653 632 71182 G168 T E A E A P D G S I L V N T P
Sea Urchin Strong. purpuratus XP_796055 760 83393 G259 K G G A N Y P G V T Q E N I G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36102 679 76436 N215 P P P I E S S N L K Y P R I Y
Red Bread Mold Neurospora crassa Q7SDP4 656 73993 L192 L A G A G A G L Y Q P A G F G
Conservation
Percent
Protein Identity: 100 99.8 99.7 74.4 N.A. 90.1 82.2 N.A. 80.8 78.3 58.4 68.2 N.A. 38.5 41.8 31.9 49.3
Protein Similarity: 100 100 99.8 74.7 N.A. 90.9 83 N.A. 86 84.1 64 75 N.A. 55.7 59.6 49.5 62.6
P-Site Identity: 100 100 100 100 N.A. 6.6 86.6 N.A. 0 73.3 13.3 13.3 N.A. 20 13.3 0 0
P-Site Similarity: 100 100 100 100 N.A. 20 86.6 N.A. 13.3 80 33.3 20 N.A. 33.3 20 0 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21.7 28
Protein Similarity: N.A. N.A. N.A. N.A. 42.1 45.2
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 0
P-Site Similarity: N.A. N.A. N.A. N.A. 20 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 25 7 19 13 13 0 0 13 7 0 19 13 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 7 0 0 13 0 0 0 0 0 0 0 0 % D
% Glu: 0 7 0 7 7 7 0 0 0 0 0 7 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 7 13 0 % F
% Gly: 7 7 19 0 13 0 13 13 0 13 7 44 7 0 13 % G
% His: 0 0 13 0 0 0 0 0 0 0 13 0 7 0 0 % H
% Ile: 0 0 0 13 0 0 0 0 0 7 0 0 0 19 44 % I
% Lys: 13 0 0 7 0 0 7 0 0 7 0 0 0 0 0 % K
% Leu: 7 0 0 0 0 7 0 7 7 0 7 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 7 0 13 0 7 % M
% Asn: 7 32 38 0 7 0 0 7 7 0 0 0 13 0 13 % N
% Pro: 7 19 7 38 19 32 19 7 50 13 7 7 0 13 13 % P
% Gln: 0 0 0 0 0 0 38 7 0 7 7 0 38 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % R
% Ser: 0 0 0 0 0 38 13 19 7 44 44 7 0 0 7 % S
% Thr: 13 0 19 13 0 0 0 38 7 7 7 0 0 13 0 % T
% Val: 38 0 0 0 38 0 0 7 7 0 0 19 0 38 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 7 7 0 0 7 0 7 0 0 7 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _